Abstract: IRS, 1H-NMR and UHPLC-Q/TOF MS were used for analysis of 3 triazolopyrimidine sulfonamide-herbicides. As shown by the IR spectra, characteristic absorption peaks of the 3 herbicides were found at 3 360-3 180, 1 630, 1 540, 1 500, 1 300, 1 150 cm-1. They could be distinguished from each other according to the change of wave number aroused from different substitute groups in the pyrimidine ring. It was shown by the 1H-NMR spectra, that characteristic shifts at δH 7.46-9.38 and δH 10.82-11.91 were due to the hydrogen atoms present in the pyrimidine ring and the sulfonamide group. They could be distinguished from each other according to the chemical shifts aroused from different substitute groups in the pyrimidine ring. As shown in the mass spectra obtained by UHPLC-Q/TOF MS, sulfaminebridging group was easy to break, and the corresponding characteristic ion fragments were produced. By co-interpretation of the spectra obtained by the above mentioned methods qualitative identification of the 3 kinds of herbicides was attained effectively.