Abstract: Brown borosilicate glass bottle of 40 mL was used to collect water sample with 4 g of mixture of sodium carbonate and sodium chloride (mass ratio of 3∶1) as salting out agent. The bottle was filled with the water sample. GC-MS was applied to the simultaneous determination of 11 ether compounds in the water sample with purge and trap. The HP-VOC chromatographic column (90 m×0.32 mm, 1.8 μm) was used for GC separation and the selected ion monitoring mode was adopted in MS determination. Fluorobenzene was used as internal standard. Linearity ranges of ethylene oxide, propylene oxide and tetrahydrofuran were found in the same range of 5.0-100 μg·L^-1 and linearity ranges of other 8 ether compounds were found in the same range of 0.50-50 μg·L^-1, with detection limits in the range of 0.113-2.62 μg·L^-1. On the base of blank sample of terminal tap water, test for recovery was made by standard addition method; values of recovery found were in the range of 85.3%-115%, with RSDs (n=6) of determined values in the range of 3.0%-9.4%.