Abstract: A method for determination of 8 heavy metal elements, including chromium, cobalt, nickel, cadmium, antimony, thallium, lead, and manganese, and arsenic in human blood by microwave digestion-inductively coupled plasma mass spectrometry (ICP-MS) with standard addition method was proposed. 1 mL of blood sample was taken and placed in a digestion tank. 10 μL of 6.25 mg·L^{-1 115}In internal standard solution and 8 mL of 70% (volume fraction) nitric acid solution were added. The digestion tank was closed and placed in a microwave digestion instrument for digestion. After cooling, the solution was placed in an acid removal device to remove acid for 2 h and the digestion solution was placed in a 25 mL-volumetric flask. The digestion tank was washed with water 3 times and the cleaning solution was placed in the same volumetric flask. The solution was made its volume with water and determined by ICP-MS, with the standard addition method for quantification. As shown by the results, linear relationships between the ratios of the corresponding response intensity to the internal standard response intensity and the reciprocal of the mass concentration of 9 elements were kept in definite ranges, with detection limits (3s) in the range of 0.006 3-0.068 4 μg·L^-1. In the test for recovery, giving results in the range of 84.4%-117%. RSDs of the determined values obtained from intra-day (n=11) and inter-day (n=3) precision tests were less than 4.0%. This method was used for the analysis of 3 healthy human blood samples, the elements with lower levels in the human body, such as arsenic, cadmium, antimony, were consistent with literature reports.