Abstract: Tungsten ore is an important strategic material, and establishing a simple, rapid, and accurate method for determining the content of 10 components in tungsten ore plays a crucial role in ore beneficiation. Therefore, the research mentioned by the title was conducted. The 8.000 0 g of mixture flux of sodium tetraborate and lithium tetraborate at mass ratio of 3∶7, and 0.100 0 g of tantalum pentoxide (the internal standard for tungsten trioxide), and 0.400 0 g of pre-dried sample were placed in a platinum-gold crucible. The mixture was stirred evenly, and pre-oxidized at 650 ℃ for 30 min. Then, 12 drops of the 300 g · L^-1 lithium iodide solution were added, and the mixture was melted at 1 050 ℃ for 19 min. The major and minor components in prepared sample pellets were analyzed using X-ray fluorescence spectrometry. Determination data of silicon, aluminum, calcium, magnesium, iron, titanium, phosphorus, manganese, and potassium were corrected using correction formulas based on the fundamental parameter method. The issues of poor linearity of the tungsten trioxide calibration curve and low determination accuracy were eliminated using the tantalum internal standard method. It was shown that linear relationships between the mass fractions of 10 components and the fluorescence intensity ratio of tungsten to tantalum (tungsten trioxide) or fluorescence intensities (the other 9 components) were kept in definite ranges, with detection limits (3s) in the ranges of 10.00-48.00 mg·kg^-1 for manganese, titanium, and phosphorus, and 0.010%-0.12% for the remaining 7 components. This method was applied to the 12 times repeated determination of 10 components in tungsten ore reference material GBW07241, polymetallic ore reference material GBW07369, and 2 actual samples. The determined values were basically consistent with the certified values, and RSDs were all less than 7.0%. The determination results of 10 components in the actual samples were in good agreement with the data obtained by traditional chemical methods.