Abstract: Based on a thorough study on the selection of analytical spectral lines and on the interference of the matrix element nickel,a method of simultaneous determination of the alloying elements,i.e.,Cr,Ti,Nb,Al,Fe and B,in nickel base high-temperature alloy by ICP-AES was proposed.Detection limit (3s/k) of the method for the 6 elements were found in the range of 0.006 9-0.13 mg·L-1. A standard sample of GH 33 nickel-base high-temperature alloy was analyzed by the proposed method for contents of the 6 elements,giving the determined values in consistency with the standard values and values of RSD′s (n=10) less than 1.5%.Recovery of the method was tested by addition of mixed standard solution to solutions containing matrix solution of nickel,giving values of recovery in the range of 98.3%-101.0%.The accuracy of the proposed method was further tested by analyzing a sample of GH 4145 nickel-base high-temperature alloy,the results obtained were in consistency with those found by methods of the national standards.