Abstract: The research progress of the extraction, separation and detection of arsenic was showed in this review, including the common extraction methods, such as ultrasonic extraction, microwave assisted extraction and solid phase extraction; the co-precipitation and capillary electrophoresis used for enrichment of arsenic in water and seafood samples respectively; the methods of separation and detection for arsenic speciation analysis, such as HPLC-ICP-MS, HPLC-HG-AAS, HG-ICP-AES, etc (56 ref. cited).