Abstract: GC with headspace-solid phase micro-extraction (HS-SPME) was applied to the determination of residual amounts of commonly used solvents in cigarette packaging materials. To attain a higher efficiency in SPME, the 75 μm CAR/PDMS fiber as coating was selected for the micro-extractor, the extraction was carried out at 100 ℃ for 40 min, and desorption was carried out at 200 ℃ for 10 min. The analyte were separated on DB-1 quartz capillary column and detected by flame ionization detector. Tests for recovery were made by standard addition method, the results of recovery obtained were ranged from 79% to 92%, with RSD′s (n=7) in the range of 4.2%-5.8%.