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    用电感耦合等离子体质谱法测定中草药中重金属元素

    Determination of Heavy Metal Elements in Chinese Traditional Herbs by ICP-MS

    • 摘要: 建立了用电感耦合等离子体质谱法(ICP-MS)测定中草药中重金属元素(砷、铅、镉、铬、汞、镍)的方法.中草药样品用硝酸和过氧化氢经微波消解后,消化液直接用ICP-MS同时测定6种重金属元素.以钪、钇、铟和铋作为内标物质,补偿了基体效应;选择适当的待测元素同位素克服了质谱干扰;6种重金属元素的检出限在0.001~0.006 μg·L-1之间,回收率在90%~107%之间,相对标准偏差小于3.2%.

       

      Abstract: An ICP-MS method was proposed for the determination of heavy metal elements: As,Pb,Cd,Cr,Hg and Ni in Chinese traditional herbs.The herb sample was digested with HNO3-H2O2 in a closed vessel in microwave digestor.The analytes in the sample solution were then determined by ICP-MS.Sc,Y,In and Bi were selected as the internal standards to compensate matrix effects.Approprate isotopes of the elements determined were selected to eliminate MS interferences.Working conditions were optimized.DL of the analytes was in range of 0.001-0.006 μg·L-1.Recovery were in the range of 90%-107% and RSD′s found were less than 3.2%.

       

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