Abstract: The contents of Pb,As,Cd,Cr,Ni and Hg in cigarette smoke were determined by ICP-MS.The HNO3 solution was used as trapping agent,and self-made absorber was used to absorb cigarette smoke.Matrix effect was corrected with mixed standard solution of Sc,Y,In and Bi as online internal standard,and spectral interferences were eliminated by choosing suitable isotopes of elements to be measured.Detection limits (3s/k) of the 6 elements were less than 0.01 μg·L.The proposed method was applied in the analysis of 4 kinds of cigarette samples,giving values of recovery in the range of 89%-103%,and RSD′s (n=5) in the range of 2.4%-3.4%.