Abstract: HPLC-MS/MS was applied to the determination of residual amounts of 6 triazine herbicides (i.e., atrazine, prometryne, simazine, ametryn, propazine and simetryn) in fruits and vegetables. The sample was extracted with acetonitrile and purified by addition of PSA adsorbent. The supernatant was used for HPLC-MS/MS analysis. Shiseido C18 column was used as stationary phase, and mixtures of acetonitrile and 0.02 mol·L-1 ammonium acetate solution mixed in different ratios were used as mobile phase in gradient elution. ESI+ as well as multi-reactions monitoring was adopted in MS/MS. Linear relationships between values of peak area and mass concentration of the 6 triazine herbicides were obtained in the same range of 1-20 μg·L-1, with same detection limits (3S/N) of 0.005 mg·kg-1. Tests for recovery and precision were made by addition of 0.008, 0.02 and 0.04 mg·kg-1 of mixed standard solution of the 6 triazine herbicides, giving values of recovery in the range of 85.8%-97.8% and values of RSD′s(n=10)in the range of 3.6%-11%.