Abstract: The sample of melaminoplastic tableware was soaked with 4 kinds of food simulacrums, including distilled water, alcohol (10+90), 30 g·L-1 acetic acid and oliver oil, and melamine monomer in the solution obtained was determined by HPLC. Conditions of temperature, time, number of times of soaking and microwave power were studied. It was found that the value of lower limit of determination of monomer melamine was same to be 0.025 mg·L-1. Under the condition of same time and temperature of soaking, the amount of monomer melamine migrated decreased sequentially as soaked separately in 30 g·L-1 acetic acid, alcohol (10+90), distilled water and olive oil; however, the difference of amount of melamine monomer migrated between distilled water and alcohol (10+90) was not obvious. The amount of melamine monomer migrated increased with increase of soaking time, soaking temperature and microwave power. Furthermore, the amount of melamine monomer migrated from the tablewares in each soaking, decreased obviously with the increase of number of times of soaking (n≥3).