Abstract: IC was applied to the determination of 8 anions and cations including F-,Cl-,NO3-,SO42-,Na+,K+,Mg2+ and Ca2+ in household drinking well water from different regions. IonPac AS11-HC separation column and IonPac AG11-HC protective column were used for separation and 30 mmol·L-1 KOH solution was used as eluent (for anion analysis);IonPac CS12A separation column and IonPac CG12A protective column were used for separation and 20 mmol·L-1 methanesulfonic acid solution was used as eluent (for cation analysis). Conductivity detection was adopted in the determination. Linear relationships between values of peak area and mass concentration of the 8 ions were kept in definite ranges. Detection limits (3s) found were ranged from 0.002 to 0.034 mg·L-1. Precision of the method was tested at the sample of well water,values of RSD′s (n=6) found was in the range of 0.59%-2.0%. Test for recovery was performed by standard addition method,giving recovery in the range of 98.3%-109%.