Abstract: A review on the recent advances of researches on methods of determination of substances of very high concern in plastic products was presented.Compound information on 4 groups of substances of very high concern,i.e.phthalate acid esters,organotin,flame retardant and perfluorinated compounds was outlined.The methods of GC,LC and MS in determination of the above substances of very high concern in plastic products were summarized.Prospects on the trends of development in this field were also given (40 ref.cited).