Simultaneous ICP-MS Determination of 17 Elements in Urine with Dynamic Reaction Cell

The urine sample was acidized with HNO₃ to 1% of volume fraction of HNO₃. After centrifugation, the supernatant was diluted 10 times with 4%(φ) HNO₃ solution. ICP-MS was applied to the simultaneous determination of 17 elements, i.e. Pb, Cd, As, Se, Mn, Cu, Zn, Sb, Be, V, Fe, Ni, Mo, Cr, Tl, Co and Sn in the solution with dynamic reaction cell. ⁴⁵Sc (for determination of Mn、Cu、Be、V、Fe、Ni、Cr、Co), ⁷²Ge (for determination of As、Se、Zn), ¹¹⁵In (for determination of Cd、Sb、Mo、Sn) and ²⁰⁹Bi (for determination of Pb、Tl) were used as internal standards. Linearity range of Fe found was in the range within 5.00 mg·L^-1and linearity ranges of the others were in the range within 50.0 μg·L^-1, with detection limits (3s) in the range of 0.000 5-0.496 0 μg·L^-1. The proposed method was applied to the analysis of urine sample, giving values of recovery and RSD's (n=7) in the ranges of 85.6%-110% and 0.68%-4.8% respectively.