Determination of 54 Fragrance Allergens in Consumer Products with Polyester Fiber Matrices by Gas Chromatography-Mass Spectrometry with Headspace

The sample was cut into small pieces, placed into a headspace bottle, extracted by cuetone, and determined by gas chromatography-mass spectrometry with headspace. In chromatographic analysis, the HP-35 low loss quartz capillary column was used as the stationary phase to separate 54 fragrance allergens under programmed temperature conditions. In mass spectrometry analysis, the electrospray ion (EI) source was used for ionization, and the selected ion monitoring mode was selected for data collection. It was shown that linear relationships between values of the mass concentration and the corresponding peak area of 54 fragrance allergens were kept in the range of 0.2-50 mg·L^-1, with lower limits of determination (10s) in the range of 0.10-1.52 mg·kg^-1. Test for recovery was made according to the standard addition method, giving recoveries in the range of 78.7%-107%, and RSDs (n=6) of the determined values ranged from 1.9% to 11%. The proposed method was applied to the analysis of 5 batches of consumer products with polyester fiber matrices, and fragrance allergens were detected in each batch of sample, with detection amounts ranged from 0.319 mg·kg^-1 to 0.884 mg·kg^-1.