Rapid Determination of Five Fragrances in Cosmetics by Headspace-Gas Chromatography-Ion Mobility Spectrometry

A method was proposed for the rapid determination of five fragrances, including ethyl acrylate, limonene, trans-2-heptenal, linalool and citral, in cosmetics by headspace-gas chromatography-ion mobility spectrometry. The cosmetic sample or the cosmetic sample diluted with water was taken, incubated at 80 ℃ for 20 min, and injected into headspace. The five fragrances were determined with mobility tube linear voltage of 400 V·cm^-1, mobility tube temperature of 45 ℃ and mobility gas flow rate of 150 mL·min^-1 in positive ion mode. As shown by the results, the linear range of the standard curve of the five fragrances was 0.1-5.0 mg·L^-1, and detection limits (3S/N) in the range of 0.02-0.05 mg·L^-1. This method was used to analyze 8 batches of cosmetics, and limonene and linalool were detected, with the detection amounts of 0.005-352 μg·g^-1. Compared with the results of conventional gas chromatography-tandem mass spectrometry, the relative deviation was in the range of -8.6% -10%.