CV Determination of p-Acetaminophenol with the Composite Film Modified Electrode of Ag-Ala/GCE

The β-alanine and silver composite film modified glassed carbon electrode (Ag-Ala/GCE) was prepared and the electrochemical property of the modified electrode vs. p-acetaminophenol (ACOP) was studied by cyclic voltammetry. It was found that ACOP showed a pair of redox peaks in PBS of pH 4.0 and based on this finding, a selectrive method for determination of ACOP by cyclic voltammetry was proposed. Linear relationship between values of peak current and concentration of ACOP was ranged from 6.0×10-7 to 7.0×10-4mol·L-1, with detection limit (3S/N) of 2.0×10-7mol·L-1. The proposed method was used in the determination of ACOP in medicament, and test for recovery was made by standard addition method, giving values of recovery in the range of 95.1%-101.6%.