Study on Interaction Between Chrysin with BSA by Linear Sweep Voltammetry

The interaction between chrysin with bovine serum albumin (BSA) was studied by linear sweepping voltammetry. The optimized conditions found were as follows: ① medium: Na2HPO4-NaH2PO4 buffer solution of pH 7.40; ② reaction time: 20 min; ③ reaction temperature: 298 K; ④ ionic strength: 1.0×10-3mol·L-1 NaCl. It was found that an electrochemically non-active supermolecular compound between chrysin and BSA was formed, with transfer coefficient (α) of 0.121 9 and apparent electron transfer rate constant (ks) of 0.914 s-1.