Assay of High-carbon Dialkyl Carbonates by HPLC-MS in Hyphenation

By the application of high performance liquid chromatography and mass spectrometry in hyphenation,satisfactory separation and assaying as well as structural identification of the main reaction product,dialkyl carbonate,produced by the reaction between low carbon alkyl carbonate and high carbon alcohol with carbon number greater than 10,was attained.The Novapak C18 column (3.9 mm×150 mm) column was used as stationary phase and absolute alcohol was used as mobile phase in chromatography with differential detector.The ion source used in mass spectrometry was the APCI.It was proved that the proposed method was feasible for supervision and control of product-quality of the process of synthesis of high-carbon dialkyl carbonates.