Linear Scanning Polarographic Determination of Eperisone Hydrochloride

It was found that in an acetate buffer solution of pH 4.73 and by the linear scanning polarography, a sensitive adsorption wave of eperisone hydrochloride was observed at the potential of -1.269 V (vs.SCE). Linear relationship between values of the 1st derivative of peak current and mass concentration of eperisone hydrochloride was obtained in the range of 0.05-250.0 mg·L-1 with detection limit (3S/N) of 0.04 mg·L-1. Precision was tested with standard solution of eperisone hydrochloride of 50.0 mg·L-1 for 6 determinations, value of RSD found was 0.98%. The proposed method has been used in the determination of content of eperisone hydrochloride in its tablets.