IC Determination of Glyoxylic Acid and Formic Acid in Reaction Medium for Preparation of Glyoxylic Acid by Oxidation of Glyoxal with Oxygen

Ion chromatography was applied to the determination of glyoxylic acid and formic acid in the reaction medium for preparation of glyoxylic acid by oxidation of glyoxal with oxygen.The YSA 8-8162A-1# anion chromatographic column was used as stationary phase,and a mixed solution containing 4.8 mmol·L-1 Na2CO3 solution and 6.0 mmol·L-1 NaHCO3 solution was used as mobile phase at the flow-rate of 1.0 mL·min-1.Conductivity detection was adopted in the analysis.Retention time of chromatographic peak was taken as a basis for qualitative testing of formic acid (tR 3.015 min) and glyoxylic acid (tR 4.282 min),and the standard curves prepared by plotting concentration of the 2 compounds against the respective values of peak area were used in the quantitative analysis.Test for recovery was made by standard addition method and values of recovery for both compounds were in the range of 98%-103%.