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    LIAN Shu-qin, YANG Dong-zhi, ZHENG Xiao-xiao, LIAN Jing, WANG Gui-rong. Study on Interaction of Gatifloxacin with Pepsin by Fluorospectrophotometry[J]. PHYSICAL TESTING AND CHEMICAL ANALYSIS PART B:CHEMICAL ANALYSIS, 2013, 49(3): 253-255.
    Citation: LIAN Shu-qin, YANG Dong-zhi, ZHENG Xiao-xiao, LIAN Jing, WANG Gui-rong. Study on Interaction of Gatifloxacin with Pepsin by Fluorospectrophotometry[J]. PHYSICAL TESTING AND CHEMICAL ANALYSIS PART B:CHEMICAL ANALYSIS, 2013, 49(3): 253-255.
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    Study on Interaction of Gatifloxacin with Pepsin by Fluorospectrophotometry

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    • The interaction between gatifloxacin (GTFX) and pepsin (PS) in a KCl-HCl medium of pH 2.0 was studied by fluorospectrophotometry. Mechanism of quenching of fluorescence of PS by GTFX was discussed, which was proved to be a process of static quenching. Quenching constant (KSV), combination constant of (K) and number of combination sites (n) at 3 different temperatures of 288 K, 298 K, 310 K were determined.
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