Page 134 - 理化检验-化学分册2024年第十二期

覃 勇，等：不饱和脂肪酸结构表征的质谱分析方法的研究进展

derivatization strategy for high-coverage quantification of fatty acids by liquid chromatography-tandem mass
free fatty acids by liquid chromatography-tandem mass spectrometry[J]. Analytica Chimica Acta，2020，1136：
spectrometry[J]. Analytical Chemistry，2017，89（22）： 187-195.
12223-12230. [48] ZHENG J，GONG G G，ZHENG S J，et al. High
[39] LIU M，WEI F，LÜ X，et al. Rapid and sensitive coverage profiling of carboxylated metabolites in
detection of free fatty acids in edible oils based on HepG2 cells using secondary amine-assisted ultrahigh-
chemical derivatization coupled with electrospray performance liquid chromatography coupled to high-
ionization tandem mass spectrometry[J]. Food resolution mass spectrometry[J]. Analytical Chemistry，
Chemistry，2018，242：338-344. 2021，93（3）：1604-1611.
[40] HU T，TIE C，WANG Z，et al. Highly sensitive and [49] WEI J T，XIAO X J，LI K，et al. Derivatization strategy
specific derivatization strategy to profile and quantitate for semi-quantitative analysis of medium- and long-chain
eicosanoids by UPLC-MS/MS[J]. Analytica Chimica fatty acids using multiple reaction monitoring[J]. Talanta，
Acta，2017，950：108-118. 2021，233：122464.
[41] NARAYANA V K，TOMATIS V M，WANG T， [50] CHENG J，LI Y L，WANG Y J，et al. Quaterization
et al. Profiling of free fatty acids using stable isotope derivatization with bis（pyridine）iodine tetrafluoroboride：
tagging uncovers a role for saturated fatty acids in High-sensitivity mass spectrometric analysis of unsaturated
neuroexocytosis[J]. Chemistry & Biology，2015，22（11）： fatty acids in human thyroid tissues[J]. Analytical
1552-1561. Chemistry，2022，94（32）：11185-11191.
[42] LENG J P，GUAN Q，SUN T Q，et al. Application [51] MA X X，XIA Y. Pinpointing double bonds
of isotope-based carboxy group derivatization in LC- in lipids by Paternò-Büchi reactions and mass
MS/MS analysis of tissue free-fatty acids for thyroid spectrometry[J]. Angewandte Chemie International
carcinoma[J]. Journal of Pharmaceutical and Biomedical Edition，2014，53（10）：2592-2596.
Analysis，2013，84：256-262. [52] MA X X，CHONG L，TIAN R，et al. Identification
[43] LENG J P，WANG H Y，ZHANG L，et al. A highly and quantitation of lipid C=C location isomers：A
sensitive isotope-coded derivatization method and its shotgun lipidomics approach enabled by photochemical
application for the mass spectrometric analysis of analytes reaction[J]. Proceedings of the National Academy of
containing the carboxyl group[J]. Analytica Chimica Sciences of the United States of America，2016，113（10）：
Acta，2013，758：114-121. 2573-2578.
[44] LENG J P，GUAN Q，SUN T Q，et al. Direct infusion [53] MA X X，ZHAO X，LI J J，et al. Photochemical tagging
electrospray ionization-ion mobility-mass spectrometry for quantitation of unsaturated fatty acids by mass
for comparative profiling of fatty acids based on stable spectrometry[J]. Analytical Chemistry，2016，88（18）：
isotope labeling[J]. Analytica Chimica Acta，2015，887： 8931-8935.
148-154. [54] XIE X B，XIA Y. Analysis of conjugated fatty acid
[45] NEUBER C，SCHUMACHER F，GULBINS E， isomers by the Paternò-Büchi reaction and trapped ion
et al. Method to simultaneously determine the mobility mass spectrometry[J]. Analytical Chemistry，
sphingosine 1-phosphate breakdown product（2E）- 2019，91（11）：7173-7180.
hexadecenal and its fatty acid derivatives using isotope- [55] TANG F，GUO C G，MA X X，et al. Rapid in situ
dilution HPLC-electrospray ionization-quadrupole/time- profiling of lipid C=C location isomers in tissue
of-flight mass spectrometry[J]. Analytical Chemistry， using ambient mass spectrometry with photochemical
2014，86（18）：9065-9073. reactions[J]. Analytical Chemistry，2018，90（9）：5612-
[46] LA NASA J，DEGANO I，BRANDOLINI L， 5619.
et al. A novel HPLC-ESI-Q-ToF approach for the [56] CHONG L，TIAN R，SHI R Y，et al. Coupling the
determination of fatty acids and acylglycerols in food Paternò-Büchi（PB）reaction with mass spectrometry to
samples[J]. Analytica Chimica Acta，2018，1013：98- study unsaturated fatty acids in mouse model of multiple
109. sclerosis[J]. Frontiers in Chemistry，2019，7：807.
[47] ZHENG J Y，JIN Y Y，SHI Z Q，et al. Fluorous- [57] ESCH P，HEILES S. Charging and charge switching of
paired derivatization approach towards highly sensitive unsaturated lipids and apolar compounds using Paternò-
and accurate determination of long chain unsaturated Büchi reactions[J]. Journal of the American Society for

• 1328 •